Ion-exchange chromatography is a common intermediate step in a protein purification protocol. Adding multi-angle light scattering in-line to preparative ion-exchange chromatography (pIEX-MALS) allows absolute molar mass determination of the eluting fractions in the course of the run, providing immediate identification of pure fractions, for optimal pooling with minimal time and effort.

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miniDAWN®

miniDAWN®

The Best in Basic Multi-Angle Light Scattering for Absolute Macromolecular Analysis.

The miniDAWN’s performance is exceeded only by the DAWN which covers a wider range of size and molecular weight, with even better sensitivity and additional optional modules.

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Optilab

Optilab

Universal Detection for Chromatography and FFF Separations

Using a combination of cutting-edge semiconductor photodiode technology and proprietary computer algorithms, the Optilab achieves an unprecedented combination of sensitivity and range. These features mean that it addresses both standard chromatographic applications and some challenges unique to light scattering measurements such as high concentrations, determination of sample refractive increments (dn/dc) and solvent refractive index.

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