The fundamental physical principles of light scattering employed in a DAWN® or miniDAWN® multi-angle light scattering (MALS) instrument enable low molecular
weight materials to be characterized effectively without the need for column calibration or reference standards. Thanks to their advanced electro-optical design, samples with molecular weights below two thousand Daltons can be measured easily and with remarkable precision.

The DAWN’s multi-angle detection system means that accurate molecular weights can be determined—even from samples which produce low signal levels, whether they are ultra-low-concentration high-MW molecules or higher concentrations of low-MW molecules. Since each and every detector contributes to the molecular weight calculation, the result is more sensitive and precise than that produced by any single or dual angle instrument. This is particularly important for low molecular weights where the signal may be only slightly above the background produced by scattering from the solvent.

DAWN®

DAWN®

The world’s most advanced light scattering instrument for absolute characterization of proteins, conjugates, macromolecules, and nanoparticles.

The DAWN and its companion Optilab dRI detector are the established benchmarks for MALS analysis, cited in thousands of peer-reviewed publications. Multi-angle light scattering detection is indispensable for use with GPC and HPLC-SEC in order to obtain reliable molecular mass distributions and information on molecular conformation, branching ratio, fragments and aggregates.

miniDAWN®

miniDAWN®

The Best in Basic Multi-Angle Light Scattering for Absolute Macromolecular Analysis.

The miniDAWN’s performance is exceeded only by the DAWN which covers a wider range of size and molecular weight, with even better sensitivity and additional optional modules.