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The Agitator/Stirrer for the GERSTEL MultiPurpose Sampler (MPS) can either operate in agitation or stirring mode using conventional magnetic stir bars. Stirring helps efficiently mixing heterogeneous or viscous samples, accelerates equilibration for headspace sampling and extends the lifetime of SPME fibers.
The most powerful and versatile software available for the characterization of macromolecules and nanoparticles via multi-angle and dynamic light scattering.
Performing Solid Phase Extraction (SPE) manually can be time consuming and nerve-racking, especially when recovery and reproducibility are lacking due to sample variability. If SPE can be reliably automated, it becomes a much more efficient and reproducible process.
The Sample ID (SID) 1D/2D Barcode reader for the GERTEL MultiPurpose Sampler (MPS) uses a dual camera setup and image analysis for positive identification of samples. SID can be connected to a PC or via LAN using USB connectivity.
Fully implemented into the MAESTRO software, SID enables independent sample logging or fully integrated sample ID transfer to the data file with multiple user-defined options for sample verification and the handling of deviations.
CALYPSO software is a versatile, unique tool for characterizing a wide range of molecular interactions quickly and reliably using composition-gradient, multi-angle static light scattering (CG-MALS). The CALYPSO software integrates smart method design, simple hardware manipulation, and robust data acquisition for a smooth experimental run.
Once the measurement is complete, the intuitive graphical user interface steps the user through data processing for rapid but powerful analysis of macromolecular interactions. Learn how you can explore the interactions between your macromolecules.
Label-free, immobilization-free characterization of protein-protein and other macromolecular interactions with composition-gradient multi-angle light scattering.
The Calypso® II, in conjunction with a DAWN® or miniDAWN® MALS detector, measures binding affinities and absolute, molecular stoichiometries of complex biomolecular interactions.
The GERSTEL CF200 is a powerful centrifuge for the GERSTEL MultiPurpose Sampler (MPS Robotic). The CF200 performs centrifugation of up to 6 samples at up to 4500 rpm/2000g. Centrifugation power can be specified in rpm or in g foce using the GERSTEL MAESTRO Software.
The GERSTEL Cooled Agitator is a modified version of the standard 6 position agitator used with the MultiPurpose Autosampler. It incorporates a Peltier based cryostat that allows samples can be cooled down to 10C and is also useful when stable ambient temperature are required.
The world’s most advanced light scattering instrument for absolute characterization of proteins, conjugates, macromolecules, and nanoparticles.
The DAWN and its companion Optilab dRI detector are the established benchmarks for MALS analysis, cited in thousands of peer-reviewed publications. Multi-angle light scattering detection is indispensable for use with GPC and HPLC-SEC in order to obtain reliable molecular mass distributions and information on molecular conformation, branching ratio, fragments and aggregates.
Extraction in Seconds
DPX is a fast and efficient SPE technique used for a wide rnge of applications such as drugs of abuse, therapeutic drug monitoring, comprehensive screening, pharmacology studies (NNK), as well as pesticides in fruit and vegetables. DPX is based on unique and patented SPE devices: Pipette tips that incorporate loosely contained sorbent material, which is mixed with the sample solution. Turbulent air bubble mixing creates a suspension of sorbent in the sample ensuring optimal contact and highly efficient extraction. The extraction is performed much faster than with traditional SPE techniques.
Mass Spectrometers are continuously being improved and have become so sensitive that carryover is constantly an issue. To meet today’s requirements for fast, clean and reproducible LC/MS injection; GERSTEL is now offering the LC/MS-Tool for the GERSTEL MultiPurpose Sampler MPS robotic.
Versatile separations of polymers, proteins, colloids, and nanoparticles.
The Eclipse™ AF4 supports all AF4 techniques except Hollow-Fiber Flow Field-Flow Fractionation (HF5), which is covered by the Eclipse DualTec. However, the Eclipse AF4 supports the fritless AF4 channel which prevents the difficulties encountered by certain samples prone to aggregation at the relatively high concentrations typical of the AF4 focusing step. It also supports the semi-preparative channel.
The ultimate separation system for proteins, polymers and nanoparticles.
Flow Field-Flow Fractionation is a uniquely versatile means of size-based separations, capable of fractionating and characterizing proteins and aggregates, liposomes, emulsions, viral particles, polysaccharides, nanoparticles, polymer latex particles, colloidal soil suspensions, chemical mechanical polishing slurries, and many more – with no stationary phase and almost no shear.
Automated Filtration Using The MPS
Suspended particles and matrix material in a sample can significantly influence analysis results and system suitability. Removing particulate matter from a sample or extract prior to analysis is therefore critical for many GC/MS- and LC/MS analysis methods, particularly when large series of samples must be analyzed automatically.
In LC/MS, we work hard to reach the goal of achieving the perfect LC separation and combining it with the most efficient ionization and lowest achievable MS detection limits for our analytes.
The LC separation may require a certain pH and polarity range of the eluent, while analyte ionization in the LC/MS ionization source requires yet another pH, a different buffer – or even derivatization of the analyte for best possible efficiency or optimized spectral information. How to optimize both? The logical answer is to take the effluent from the perfect LC separation and optimize it for MS analysis.
GERSTEL SPEXOS expands your sample preparation portfolio with online SPE. Compared with sandard SPE, SPEXOS relies on much smaller cartridges with only 50 mg of sorbent, enabling a significant miniaturization of the entire process: Much smaller sample amounts are needed to reach required detection limits and much less solvent is needed for analyte elution reducing cost, simplifying logistics, and increasing method sensitivity.
GERSTEL provides a wide range of cooled trays and stacks for the MPS Robotic series either as part of an analysis system or as an off-line WorkStation. Trays and stacks available with Peltier cooling or cryostatic cooling covering a temperature range from 4 to 70C.
The MAESTRO software operates all GERSTEL modules and system solutions in a simple and efficient manner. MAESTRO can be operated as stand-alone software or fully integrated with the Agilent Technologies ChemStation. Just one method and one sequence table runs the complete system from Sample Prep and Sample Introduction to GC/MS or LC/MS analysis. Set-up is performed in a very simple manner: By mouse-click.
Water analysis can be complicated if the sample contains a large proportion of suspended substances and foreign particles.
Membrane extraction promises simplification in this case: a novel procedure for sample preparation developed by the Environmental Research Centre Leipzig-Halle, which has been automated by GERSTEL.
The microDAWN MALS detector performs absolute characterization of macromolecules eluting from UHPLC, determining molar mass and size independently of retention time and molecular reference standards.
This instrument offers superb sensitivity over a wide range of molar mass, size and concentrations. In most respects the microDAWN is similar to the well-established miniDAWN , a workhorse MALS instrument used in hundreds of labs around the world for characterizing proteins and other molecules smaller than 50 nm in radius.
Refractive index detection is an important component of any SEC-MALS system, and necessary for analyzing conjugated proteins or polymers devoid of chromaphores. The microOptilab connects with the microDAWN MALS detector for a complete UHP-SEC-MALS setup that transfers the many benefits of SEC-MALS analysis to the realm of UHPLC.
The microViscoStar™ incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for UHPLC. Its ease-of-use and serviceability make it the perfect companion for Wyatt’s microDAWN™ light scattering and microOptilab™ refractive index detectors for UHPLC.
The Best in Basic Multi-Angle Light Scattering for Absolute Macromolecular Analysis.
The miniDAWN’s performance is exceeded only by the DAWN which covers a wider range of size and molecular weight, with even better sensitivity and additional optional modules.
Fully automated solvent evaporation integrated with your sample preparation.
The GERSTEL Multi-Position Evaporation Station (mVAP) performs solvent evaporation enabling automated sample concentration for lower detection limits as well as solvent exchange for improved chromatography and LC/MS ionization. mVAP is an option for the GERSTEL MultiPurpose Sampler (MPS): Up to 196 samples in standard autosampler vials can be concentrated in batches of up to six.
OBSERVER acquires real-time multi-angle light scattering data from ultraDAWN, then calculates and reports weight-average molar mass and z-average rms radius, thirty times each minute.
Where most PAT instruments monitor process conditions such as temperature, pressure and feedstock, OBSERVER’s RT-MALS analysis provides actual product quality attributes. When the RT-MALS results deviate from specifications or reach the process end point, OBSERVER can send a trigger to control the process, directly or indirectly via OPC.
Using a combination of cutting-edge semiconductor photodiode technology and proprietary computer algorithms, the Optilab achieves an unprecedented combination of sensitivity and range. These features mean that it addresses both standard chromatographic applications and some challenges unique to light scattering measurements such as high concentrations, determination of sample refractive increments (dn/dc) and solvent refractive index.
quickMix for the GERSTEL MPS Robotic series enables extremely fast and efficient mixing nad extraction of samples as part of the automated sample preparation process.
The mixing power is comparable to that of vortex mixing. Samples are agitated in a special tray on the module, depending on the vial size holding up to 6 samples at a time. The tray can be exchanged to operate with 2 mL, 4 mL, 10 mL and 20 mL vials. If needed, quickMix can be configured with a heated tray.
The MPS Robotic is a highly efficient GC/MS and LC/MS autosampler with extended robotic functionality. The MPS robotic provides reliable and efficient processing of complex tasks. Syringes are mounted in individual syringe modules, which be exchanged automatically within a running sequence when using the MPS RoboticPro for maximum flexibility.
Twister® Back Extraction as MPS Option
The combination of Twister technology (SBSE; Stir Bar Sorptive Extraction) with elution and subsequent chromatographic detection can be powerful and reproducible process for the determination of organic analytes from aqueous samples; e.g. PAH, psticides, herbicides or phenols.
A breakthrough in process analytical technology for production of nanoparticles, biopharmaceuticals and polymers.
ultraDAWN measures multi-angle light scattering and reports the results – weight-average molecular weight Mw and rms radius Rg – in real time. With RT-MALS, critical quality attributes (CQAs) can be monitored directly, for rapid feedback on product and process quality.
The ViscoStar® incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for GPC. Its ease-of-use and serviceability make it the perfect companion for Wyatt’s DAWN® light scattering and Optilab® refractive index detectors.
Flatten the learning curve and increase your productivity. Wyatt offers a suite of unmatched software tools for designing, performing and analyzing FFF-MALS experiments.
For maximum convenience, use the VISION CSH® software hub to launch Wyatt’s native FFF method development, instrument control and data analysis packages: SCOUT DPS®, VOYAGER CDS® and ASTRA®.
Eclipse FFF systems can also be controlled from plug-ins residing within industry-standard HPLC software. If you are familiar with OpenLab®, ChemStation®, Chromeleon® or LabSolutions®, easily set up enhanced.
Standard autosampler vials are placed in the balanec by the MPS and liquid samples, stnadards, reagents or diluents added, weighed and registered separately. For each sample, mulitple liquid additions can be defined by mouse-click in the MAESTRO Software.
Flexible and reliable sample preparation robot providing efficient automation of your laboratory processes.
The GERSTEL MuliPurpose Sampler (MPS) provides a wide range of capabilities in one robotic system. The MPS WorkStation is a bench-top version of the MPS, independent of the GC/MS or LC/MS analysis system. The WorkStation can be configured as Single Head or Dual Head version enabling it to perform a range of functions to meet almost every requirements in terms of performance and throughput. The MPS WorkStation provides complete flexiblity. In combination with the GERSTEL MAESTRO software, the MPS WorkStation offers simple set-up and advanced automation capabilities.