Showing all 15 results

ASTRA

ASTRA

Turn your data into results with the ultimate in light scattering software—ASTRA.

The most powerful and versatile software available for the characterization of macromolecules and nanoparticles via multi-angle and dynamic light scattering.

  • Maximize your productivity via ASTRA’s One-Click MW™ feature, automated multi-sequence processing and HPLC integration.
  • Take advantage of its integrated control of Agilent systems, or its support for Waters Empower sequences.
  • ASTRA offers a suite of basic and advanced analyses, including customized reports and an optional 21CFR(11)-compliant security and database package.
  • It greatly simplifies MALS and DLS analysis, so you can quickly and accurately assess molar mass, size, conformation, conjugation and other essential physical parameters.
  • With each analysis, ASTRA provides the quantitative experimental uncertainties that transform mere numbers—into science.
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CALYPSO

CALYPSO

Comprehensive Interaction Analysis.

CALYPSO software is a versatile, unique tool for characterizing a wide range of molecular interactions quickly and reliably using composition-gradient, multi-angle static light scattering (CG-MALS). The CALYPSO software integrates smart method design, simple hardware manipulation, and robust data acquisition for a smooth experimental run.

Once the measurement is complete, the intuitive graphical user interface steps the user through data processing for rapid but powerful analysis of macromolecular interactions. Learn how you can explore the interactions between your macromolecules.

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Calypso II CG-MALS

Calypso II CG-MALS

Label-free, immobilization-free characterization of protein-protein and other macromolecular interactions with composition-gradient multi-angle light scattering.

The Calypso® II, in conjunction with a DAWN® or miniDAWN® MALS detector, measures binding affinities and absolute, molecular stoichiometries of complex biomolecular interactions.

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DAWN®

DAWN®

The world’s most advanced light scattering instrument for absolute characterization of proteins, conjugates, macromolecules, and nanoparticles.

The DAWN and its companion Optilab dRI detector are the established benchmarks for MALS analysis, cited in thousands of peer-reviewed publications. Multi-angle light scattering detection is indispensable for use with GPC and HPLC-SEC in order to obtain reliable molecular mass distributions and information on molecular conformation, branching ratio, fragments and aggregates.

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Eclipse AF4

Eclipse AF4

Versatile separations of polymers, proteins, colloids, and nanoparticles.

The Eclipse™ AF4 supports all AF4 techniques except Hollow-Fiber Flow Field-Flow Fractionation (HF5), which is covered by the Eclipse DualTec. However, the Eclipse AF4 supports the fritless AF4 channel which prevents the difficulties encountered by certain samples prone to aggregation at the relatively high concentrations typical of the AF4 focusing step. It also supports the semi-preparative channel.

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Eclipse DualTec

Eclipse DualTec

The ultimate separation system for proteins, polymers and nanoparticles.

Flow Field-Flow Fractionation is a uniquely versatile means of size-based separations, capable of fractionating and characterizing proteins and aggregates, liposomes, emulsions, viral particles, polysaccharides, nanoparticles, polymer latex particles, colloidal soil suspensions, chemical mechanical polishing slurries, and many more – with no stationary phase and almost no shear.

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microDAWN®

microDAWN®

The microDAWN MALS detector performs absolute characterization of macromolecules eluting from UHPLC, determining molar mass and size independently of retention time and molecular reference standards.

This instrument offers superb sensitivity over a wide range of molar mass, size and concentrations. In most respects the microDAWN is similar to the well-established miniDAWN , a workhorse MALS instrument used in hundreds of labs around the world for characterizing proteins and other molecules smaller than 50 nm in radius.

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microOptilab

microOptilab

Universal Detection for UHPLC and SEC-MALS

Refractive index detection is an important component of any SEC-MALS system, and necessary for analyzing conjugated proteins or polymers devoid of chromaphores. The microOptilab connects with the microDAWN MALS detector for a complete UHP-SEC-MALS setup that transfers the many benefits of SEC-MALS analysis to the realm of UHPLC.

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microViscoStar

microViscoStar

microViscoStar: Online differential viscometer for UHPLC.

The microViscoStar™ incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for UHPLC. Its ease-of-use and serviceability make it the perfect companion for Wyatt’s microDAWN™ light scattering and microOptilab™ refractive index detectors for UHPLC.

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miniDAWN®

miniDAWN®

The Best in Basic Multi-Angle Light Scattering for Absolute Macromolecular Analysis.

The miniDAWN’s performance is exceeded only by the DAWN which covers a wider range of size and molecular weight, with even better sensitivity and additional optional modules.

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OBSERVER

OBSERVER

Real-time process monitoring and control software for ultraDAWN

OBSERVER acquires real-time multi-angle light scattering data from ultraDAWN, then calculates and reports weight-average molar mass and z-average rms radius, thirty times each minute.

Where most PAT instruments monitor process conditions such as temperature, pressure and feedstock, OBSERVER’s RT-MALS analysis provides actual product quality attributes. When the RT-MALS results deviate from specifications or reach the process end point, OBSERVER can send a trigger to control the process, directly or indirectly via OPC.

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Optilab

Optilab

Universal Detection for Chromatography and FFF Separations

Using a combination of cutting-edge semiconductor photodiode technology and proprietary computer algorithms, the Optilab achieves an unprecedented combination of sensitivity and range. These features mean that it addresses both standard chromatographic applications and some challenges unique to light scattering measurements such as high concentrations, determination of sample refractive increments (dn/dc) and solvent refractive index.

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ultraDAWN®

ultraDAWN®

A breakthrough in process analytical technology for production of nanoparticles, biopharmaceuticals and polymers.

ultraDAWN measures multi-angle light scattering and reports the results – weight-average molecular weight Mw and rms radius Rg – in real time. With RT-MALS, critical quality attributes (CQAs) can be monitored directly, for rapid feedback on product and process quality.

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ViscoStar

ViscoStar

ViscoStar: The next generation online differential viscometer.

The ViscoStar® incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for GPC. Its ease-of-use and serviceability make it the perfect companion for Wyatt’s DAWN® light scattering and Optilab® refractive index detectors.

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VISION

VISION

Field-Flow Fractionation for the most versatile separations of complex fluids.

Flatten the learning curve and increase your productivity. Wyatt offers a suite of unmatched software tools for designing, performing and analyzing FFF-MALS experiments.

For maximum convenience, use the VISION CSH® software hub to launch Wyatt’s native FFF method development, instrument control and data analysis packages: SCOUT DPS®, VOYAGER CDS® and ASTRA®.

Eclipse FFF systems can also be controlled from plug-ins residing within industry-standard HPLC software. If you are familiar with OpenLab®, ChemStation®, Chromeleon® or LabSolutions®, easily set up enhanced.

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